GPRC5B |
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Identifiers |
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Aliases | GPRC5B, RAIG-2, RAIG2, G protein-coupled receptor class C group 5 member B |
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External IDs | OMIM: 605948; MGI: 1927596; HomoloGene: 9435; GeneCards: GPRC5B; OMA:GPRC5B - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 16 (human)[1] |
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| Band | 16p12.3 | Start | 19,856,691 bp[1] |
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End | 19,886,167 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 7 (mouse)[2] |
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| Band | 7|7 F2 | Start | 118,571,270 bp[2] |
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End | 118,594,434 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - internal globus pallidus
- inferior olivary nucleus
- inferior ganglion of vagus nerve
- dorsal motor nucleus of vagus nerve
- middle frontal gyrus
- external globus pallidus
- subthalamic nucleus
- superior vestibular nucleus
- ventral tegmental area
- C1 segment
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| Top expressed in | - epithelium of lens
- deep cerebellar nuclei
- pontine nuclei
- dentate gyrus of hippocampal formation granule cell
- lobe of cerebellum
- cerebellar vermis
- saccule
- medial vestibular nucleus
- substantia nigra
- motor neuron
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - G protein-coupled receptor activity
- signal transducer activity
- protein kinase activator activity
- G protein-coupled receptor binding
- protein kinase binding
| Cellular component | - integral component of membrane
- intracellular membrane-bounded organelle
- membrane
- plasma membrane
- nucleolus
- extracellular exosome
- cytoplasmic vesicle membrane
- cytoplasmic vesicle
- nucleus
- extracellular space
- cytosol
- cell surface
- receptor complex
| Biological process | - G protein-coupled receptor signaling pathway
- signal transduction
- activation of protein kinase activity
- positive regulation of I-kappaB kinase/NF-kappaB signaling
- positive regulation of neuron differentiation
- positive regulation of inflammatory response
- positive regulation of macrophage cytokine production
- positive regulation of protein tyrosine kinase activity
- positive regulation of canonical Wnt signaling pathway
- locomotory behavior
- positive regulation of neuron projection development
- glucose homeostasis
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 16: 19.86 – 19.89 Mb | Chr 7: 118.57 – 118.59 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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