CD320

Human gene
CD320
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

4ZRP

Identifiers
AliasesCD320, 8D6, 8D6A, TCBLR, CD320 molecule, TCN2R
External IDsOMIM: 606475; MGI: 1860083; HomoloGene: 9573; GeneCards: CD320; OMA:CD320 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for CD320
Genomic location for CD320
Band19p13.2Start8,302,127 bp[1]
End8,308,358 bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for CD320
Genomic location for CD320
Band17 B1|17 17.98 cMStart34,062,065 bp[2]
End34,068,748 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • spleen

  • body of stomach

  • right lobe of thyroid gland

  • left adrenal gland

  • left coronary artery

  • fundus

  • thoracic aorta

  • ascending aorta

  • body of pancreas

  • left lobe of thyroid gland
Top expressed in
  • spermatocyte

  • spermatid

  • seminiferous tubule

  • morula

  • parotid gland

  • epithelium of stomach

  • proximal tubule

  • medial ganglionic eminence

  • otic placode

  • white adipose tissue
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • cobalamin binding
  • growth factor activity
  • ABC-type vitamin B12 transporter activity
  • protein binding
  • calcium ion binding
  • metal ion binding
Cellular component
  • integral component of membrane
  • endosome membrane
  • endoplasmic reticulum
  • membrane
  • extracellular exosome
  • integral component of plasma membrane
  • plasma membrane
Biological process
  • cobalamin metabolic process
  • regulation of vitamin metabolic process
  • cobalamin transport
  • positive regulation of B cell proliferation
  • B cell costimulation
  • regulation of signaling receptor activity
  • signal transduction
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51293

54219

Ensembl

ENSG00000167775

ENSMUSG00000002308

UniProt

Q9NPF0

Q9Z1P5

RefSeq (mRNA)

NM_016579
NM_001165895

NM_019421
NM_001305169

RefSeq (protein)

NP_001159367
NP_057663

NP_001292098
NP_062294

Location (UCSC)Chr 19: 8.3 – 8.31 MbChr 17: 34.06 – 34.07 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CD320 (cluster of differentiation 320) is a human gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167775 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000002308 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: CD320 CD320 molecule".

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Li L, Zhang X, Kovacic S, et al. (2000). "Identification of a Human Follicular Dendritic Cell Molecule That Stimulates Germinal Center B Cell Growth". J. Exp. Med. 191 (6): 1077–84. doi:10.1084/jem.191.6.1077. PMC 2193124. PMID 10727470.
  • Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Acierno JS, Kennedy JC, Falardeau JL, et al. (2001). "A physical and transcript map of the MCOLN1 gene region on human chromosome 19p13.3-p13.2". Genomics. 73 (2): 203–10. doi:10.1006/geno.2001.6526. PMID 11318610.
  • Zhang X, Li L, Jung J, et al. (2001). "The distinct roles of T cell-derived cytokines and a novel follicular dendritic cell-signaling molecule 8D6 in germinal center-B cell differentiation". J. Immunol. 167 (1): 49–56. doi:10.4049/jimmunol.167.1.49. PMID 11418631.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

  • v
  • t
  • e
1–5051–100101–150151–200201–250251–300301–350


Stub icon

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e