SA 4503

SA 4503
Nazivi
IUPAC naziv
1-[2-(3,4-Dimethoxyphenyl)ethyl]-4-(3-phenylpropyl)piperazine
Identifikacija
  • 165377-43-5
3D model (Jmol)
  • interaktivna slika
PubChem[1][2] C ID
  • 9954941
SMILES
  • COC1=C(OC)C=C(CCN2CCN(CCCC3=CC=CC=C3)CC2)C=C1
Svojstva
C23H32N2O2
Molarna masa 368,52 g·mol−1
Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje materijala (na 25 °C [77 °F], 100 kPa).
ДаY verifikuj (šta je ДаYНеН ?)
Reference infokutije

SA 4503 je agonist sigma receptora.[3][4]

Literatura

  1. ^ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today. 15 (23-24): 1052—7. PMID 20970519. doi:10.1016/j.drudis.2010.10.003.  уреди
  2. ^ Evan E. Bolton; Yanli Wang; Paul A. Thiessen; Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry. 4: 217—241. doi:10.1016/S1574-1400(08)00012-1. 
  3. ^ Matsuno K, Nakazawa M, Okamoto K, Kawashima Y, Mita S (1996). „Binding properties of SA4503, a novel and selective sigma 1 receptor agonist”. European journal of pharmacology. 306 (1-3): 271—9. PMID 8813641. doi:10.1016/0014-2999(96)00201-4. 
  4. ^ Skuza G, Rogóz Z (2006). „The synergistic effect of selective sigma receptor agonists and uncompetitive NMDA receptor antagonists in the forced swim test in rats”. J. Physiol. Pharmacol. 57 (2): 217—29. PMID 16845227. 

Spoljašnje veze

  • SA+4503 на US National Library of Medicine Medical Subject Headings (MeSH)
  • p
  • r
  • u
Modulatori sigma receptora
σ1
  • Alosterni modulatori: Fenitoin; Pozitivni: Metilfenilpiracetam
  • SOMCL-668
σ2
  • Antagonisti: AC-927
  • BD-1008
  • BD-1067
  • CM-156
  • CT-1812
  • LR-172
  • MIN-101
  • Panamesin (EMD-57455)
  • SAS-0132
Neraz-
vrstani
Portal:
  •  Hemija