Hydrocortisone buteprate
Chemical compound
- AU: A[1]
administration
- D07AB11 (WHO)
- US: OTC
- (11β)-11-hydroxy-3,20-dioxo-21-(propionyloxy)pregn-4-en-17-yl butyrate
- 72590-77-3
Y
- 636398
- DB14543 Y
- 552186
N
- O6550D6K3A
- D01886
- C13358
- CHEBI:31675
- ChEMBL200953
- DTXSID3048603
- Interactive image
- CCCC(=O)O[C@@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)O)C)C(=O)COC(=O)CC
- InChI=1S/C28H40O7/c1-5-7-24(33)35-28(22(31)16-34-23(32)6-2)13-11-20-19-9-8-17-14-18(29)10-12-26(17,3)25(19)21(30)15-27(20,28)4/h14,19-21,25,30H,5-13,15-16H2,1-4H3/t19-,20-,21-,25+,26-,27-,28-/m0/s1N
- Key:FOGXJPFPZOHSQS-AYVLZSQQSA-NN
N
Y (what is this?) (verify)Hydrocortisone buteprate, also known as hydrocortisone probutate and as hydrocortisone butyrate propionate, is a topical corticosteroid.[2][3] It is an ester of hydrocortisone (cortisol) with butyric acid and propionic acid.
References
- ^ a b "Hydrocortisone topical Use During Pregnancy". Drugs.com. 5 December 2019. Retrieved 13 September 2020.
- ^ Drugs.com: Hydrocortisone Buteprate topical
- ^ Sears HW, Bailer JW, Yeadon A (1997). "Efficacy and safety of hydrocortisone buteprate 0.1% cream in patients with atopic dermatitis". Clinical Therapeutics. 19 (4): 710–9. doi:10.1016/s0149-2918(97)80095-1. PMID 9377615.
External links
- "Hydrocortisone probutate". Drug Information Portal. U.S. National Library of Medicine.
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Medicine
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- Antagonists: Aglepristone
- Ketoconazole
- Mifepristone
- Ulipristal acetate
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Glucocorticoid receptor modulators
- Mineralocorticoids and antimineralocorticoids
- List of corticosteroids
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