Fludroxycortide
Chemical compound
- D07AC07 (WHO)
- UK: POM (Prescription only)
- 6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione
- 1524-88-5
Y
- 15209
- 7606
- DB00846 Y
- 14475 Y
- 8EUL29XUQT
- D00328 Y
- ChEMBL1201012
N
- DTXSID2047434
- Interactive image
- O=C1\C=C5/[C@](C)(CC1)[C@@H]2[C@H]([C@H]3[C@](C[C@@H]2O)([C@@]4(OC(O[C@@H]4C3)(C)C)C(=O)CO)C)C[C@@H]5F
InChI
- InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1Y
- Key:POPFMWWJOGLOIF-XWCQMRHXSA-NY
N
Y (what is this?) (verify)Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone,[1] is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).[2][3]
Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.[4][5]
References
- ^ CID 15209 from PubChem
- ^ "Fludroxycortide". Drugs.com. Archived from the original on 2019-08-29. Retrieved 2018-01-23.
- ^ "Fludroxycortide". Patient.info. 30 August 2022.
- ^ Haelan Tape Summary of Product Characteristics[permanent dead link]
- ^ Nakamura H, Motoyoshi S, Ishii K, Seto Y, Shimizu M (October 1980). "[Anti-inflammatory activity of a topical glucocorticoid, fludroxycortide tape in experimental animals (author's transl)]". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 76 (7): 595–607. doi:10.1254/fpj.76.595. PMID 7215997.
- v
- t
- e
- Antagonists: Aglepristone
- Ketoconazole
- Mifepristone
- Ulipristal acetate
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Glucocorticoid receptor modulators
- Mineralocorticoids and antimineralocorticoids
- List of corticosteroids
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