Sulbaktam

Sulbaktam
Klinički podaci


Drugs.com	Monografija
Identifikatori
CAS broj	68373-14-8^Y
ATC kod	J01CG01 (WHO)
PubChem	CID 130313
ChemSpider	115306^Y
UNII	S4TF6I2330^Y
KEGG	D08533^Y
ChEBI	CHEBI:9321^Y
ChEMBL	CHEMBL403^Y
Hemijski podaci
Formula	C₈H₁₁NO₅S
Molarna masa	233,242
SMILES CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C(=O)O
InChI InChI=1S/C8H11NO5S/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14/h5-6H,3H2,1-2H3,(H,11,12)/t5-,6+/m1/s1^Y Key:FKENQMMABCRJMK-RITPCOANSA-N^Y

Sulbaktam je organsko jedinjenje, koje sadrži 8 atoma ugljenika i ima molekulsku masu od 233,242 Da.

Osobine

Osobina	Vrednost
Broj akceptora vodonika	5
Broj donora vodonika	1
Broj rotacionih veza	1
Particioni koeficijent^[1] (ALogP)	-0,7
Rastvorljivost^[2] (logS, log(mol/L))	-1,0
Polarna površina^[3] (PSA, Å²)	100,1

^ Ghose, A.K.; Viswanadhan V.N. & Wendoloski, J.J. (1998). „Prediction of Hydrophobic (Lipophilic) Properties of Small Organic Molecules Using Fragment Methods: An Analysis of AlogP and CLogP Methods”. J. Phys. Chem. A. 102: 3762—3772. doi:10.1021/jp980230o.
^ Tetko IV, Tanchuk VY, Kasheva TN, Villa AE (2001). „Estimation of Aqueous Solubility of Chemical Compounds Using E-State Indices”. Chem Inf. Comput. Sci. 41: 1488—1493. PMID 11749573. doi:10.1021/ci000392t.
^ Ertl P.; Rohde B.; Selzer P. (2000). „Fast calculation of molecular polar surface area as a sum of fragment based contributions and its application to the prediction of drug transport properties”. J. Med. Chem. 43: 3714—3717. PMID 11020286. doi:10.1021/jm000942e.

Hardman JG, Limbird LE, Gilman AG (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10. изд.). New York: McGraw-Hill. ISBN 0071354697. doi:10.1036/0071422803.
Thomas L. Lemke; David A. Williams, ур. (2007). Foye's Principles of Medicinal Chemistry (6. изд.). Baltimore: Lippincott Willams & Wilkins. ISBN 0781768799.