Feniletanolamin N-metiltransferaza
| Feniletanolamin N-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.28 | ||||||||
| CAS broj | 9037-68-7 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Feniletanolamin N-metiltransferaza (EC 2.1.1.28, noradrenalinska N-metiltransferaza, noradrenalinska N-metiltransferaza, norepinefrin metiltransferaza, norepinefrinska N-metiltransferaza, fenetanolaminska metiltransferaza, fenetanolaminska N-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:feniletanolamin N-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + feniletanolamin S-adenozil-L-homocistein + N-metilfeniletanolamin
Ovaj enzim deluje na razne feniletanolamine. On konvertuje noradrenalin u adrenalin.
Reference
- ^ Axelrod, J. (1962). „Purification and properties of phenylethanolamine-N-methyl transferase”. J. Biol. Chem. 237: 1657—1660. PMID 13863458.
- ^ Connett, R.J. & Kirschner, N. (1970). „Purification and properties of bovine phenylethanolamine N-methyltransferase”. J. Biol. Chem. 245: 329—334. PMID 5412063.
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
- William P. Jencks (1987). Catalysis in Chemistry and Enzymology. Dover Publications. ISBN 0486654605.
Spoljašnje veze
- Phenylethanolamine+N-methyltransferase на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
Transferaze: jednougljenične transferaze (EC 2.1)
| N- |
|
|---|---|
| O- | |
| Homocistein | |
| Drugi |
formil- i srodne grupe
| Hidroksimetiltransferaza | |
|---|---|
| Formiltransferaza | |
| Drugi |
i karbamoil
| Karboksi | |
|---|---|
| Karbamoil |
- Arginin:glicin amidinotransferaza
Portali:
Molekularna i ćelijska biologija
Hemija
