Velagliflozin

Medication

  • US DailyMed: Velagliflozin
Routes of
administrationBy mouthATCvet code
  • QA10BK90 (WHO)
Legal statusLegal status
  • US: ℞-only[1]
Identifiers
  • 2-[(4-cyclopropylphenyl)methyl]-4-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]benzonitrile
CAS Number
  • 946525-65-1
PubChem CID
  • 24862817
ChemSpider
  • 58827717
UNII
  • FV2YU8SL0P
  • EQE2P2T77I
Chemical and physical dataFormulaC23H25NO5Molar mass395.455 g·mol−13D model (JSmol)
  • Interactive image
  • C1CC1C2=CC=C(C=C2)CC3=C(C=CC(=C3)[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)C#N
InChI
  • InChI=1S/C23H25NO5/c24-11-17-8-7-16(23-22(28)21(27)20(26)19(12-25)29-23)10-18(17)9-13-1-3-14(4-2-13)15-5-6-15/h1-4,7-8,10,15,19-23,25-28H,5-6,9,12H2/t19-,20-,21+,22-,23+/m1/s1
  • Key:SENUNDCNOYAWGN-ZQGJOIPISA-N
  • Key:UWKBFNWQMSGEPG-ZHNCTCHCSA-N

Velagliflozin, sold under the brand name Senvelgo, is an antidiabetic medication used for the treatment of cats.[1][2] Velagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor.[3] It is taken by mouth.[1]

Medical uses

Velagliflozin is indicated to improve glycemic control in otherwise healthy cats with diabetes not previously treated with insulin.[1][2][3]

References

  1. ^ a b c d "Senvelgo- velagliflozin solution". DailyMed. 8 November 2023. Retrieved 13 December 2023.
  2. ^ a b https://animaldrugsatfda.fda.gov/adafda/app/search/public/document/downloadFoi/14320 Public Domain This article incorporates text from this source, which is in the public domain.
  3. ^ a b "Dear Veterinarian Letter regarding important safety conditions associated with the use of Senvelgo (velagliflozin oral solution) for improving glycemic control in certain cats with diabetes mellitus". U.S. Food and Drug Administration. 4 December 2023. Retrieved 13 December 2023. Public Domain This article incorporates text from this source, which is in the public domain.
  • v
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Oral diabetes medication, insulins and insulin analogs, and other drugs used in diabetes (A10)
fast-acting
short-acting
long-acting
ultra-long-acting
inhalable
  • Exubera
  • Afrezza
Non-insulins
Insulin sensitizers
Biguanides
TZDs/"glitazones" (PPAR)
Dual PPAR agonists
Amylin analogs and DACRAs
Secretagogues
K+ATP
Sulfonylureas
Meglitinides/"glinides"
GLP-1 receptor agonists
GLP1 poly-agonist peptides
DPP-4 inhibitors/"gliptins"
Other
Aldose reductase inhibitors
Alpha-glucosidase inhibitors
SGLT2 inhibitors/"gliflozins"
Other
Combinations
  • v
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  • e
SGLT1Tooltip Sodium-glucose transporter 1
SGLT2Tooltip Sodium-glucose transporter 2
  • Antisense oligonucleotides: ISIS-388626
SGLT1Tooltip Sodium-glucose transporter 1 & SGLT2Tooltip Sodium-glucose transporter 2
See also: Receptor/signaling modulators


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