PRMT6 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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List of PDB id codes |
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4HC4, 4QPP, 4QQK, 4Y2H, 4Y30, 5EGS, 5E8R, 5HZM |
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Identifiers |
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Aliases | PRMT6, HRMT1L6, protein arginine methyltransferase 6 |
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External IDs | OMIM: 608274; MGI: 2139971; HomoloGene: 10024; GeneCards: PRMT6; OMA:PRMT6 - orthologs |
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EC number | 2.1.1.321 |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1p13.3 | Start | 107,056,674 bp[1] |
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End | 107,067,636 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3|3 F3 | Start | 110,153,425 bp[2] |
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End | 110,158,314 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gonad
- islet of Langerhans
- palpebral conjunctiva
- right adrenal cortex
- mucosa of sigmoid colon
- metanephros
- testicle
- left adrenal gland
- left adrenal cortex
- prefrontal cortex
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| Top expressed in | - renal corpuscle
- medullary collecting duct
- spermatocyte
- endocardial cushion
- epiblast
- embryo
- primitive streak
- yolk sac
- tail of embryo
- right kidney
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function | - methyltransferase activity
- transferase activity
- histone methyltransferase activity
- protein-arginine omega-N monomethyltransferase activity
- histone methyltransferase activity (H4-R3 specific)
- histone binding
- protein-arginine omega-N asymmetric methyltransferase activity
- chromatin binding
- histone methyltransferase activity (H2A-R3 specific)
- histone methyltransferase activity (H3-R2 specific)
- protein binding
- protein-arginine N-methyltransferase activity
- histone-arginine N-methyltransferase activity
| Cellular component | - nucleoplasm
- nucleus
- nucleolus
- cytosol
| Biological process | - regulation of transcription, DNA-templated
- negative regulation of transcription by RNA polymerase II
- transcription, DNA-templated
- cellular response to DNA damage stimulus
- cellular senescence
- methylation
- peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
- histone methylation
- viral process
- negative regulation of transcription, DNA-templated
- DNA repair
- base-excision repair
- protein methylation
- histone H4-R3 methylation
- regulation of megakaryocyte differentiation
- chromatin organization
- histone H3-R2 methylation
- peptidyl-arginine N-methylation
- negative regulation of histone H3-K4 methylation
- regulation of signal transduction by p53 class mediator
- histone arginine methylation
| Sources:Amigo / QuickGO |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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