Methyl hydroxychalcone
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Preferred IUPAC name 3-Hydroxy-3′-methylchalcone | |
Other names MCHP 3'-Methyl-3-hydroxychalcone | |
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Properties | |
Chemical formula | C16H14O2 |
Molar mass | 238.28 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Methyl hydroxychalcone is a chalconoid found in cinnamon. It was thought to be an insulin mimetic, improving insulin response of diabetics.[1] It has since been determined that a flavonoid (cinnamtannin B1) is responsible for the insulin-like biological activity.[2]
See also
- Anti-diabetic medication
References
- ^ Karalee J. Jarvill-Taylor, PhD; Richard A. Anderson, PhD; Donald J. Graves, PhD (August 1, 2001). "A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes". J Am Coll Nutr. 20 (4): 327–36. doi:10.1080/07315724.2001.10719053. PMID 11506060. S2CID 34049517. Archived from the original on 2004-08-11. Retrieved 2014-02-27.
- ^ Anderson; Broadhurst, CL; Polansky, MM; Schmidt, WF; Khan, A; Flanagan, VP; Schoene, NW; Graves, DJ (January 2004). "Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity". J Agric Food Chem. 52 (1): 65–70. doi:10.1021/jf034916b. PMID 14709014.
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Chalconoids and their glycosides
- Butein
- Isoliquiritigenin
- Methyl hydroxychalcone
- Okanin
- Licochalcone A
- Sophoradin (prenylated)
- Tephrospinosin (3′,5′-diisopentenyl-2′,4′-dihydroxychalcone) (prenylated)
- Xanthohumol (prenylated)
- Cardamomin
- Flavokawin B
- Okanin 3,4,3′,4′-tetramethyl ether
- Pashanone (2',6'-Dihydroxy-3',4'-dimethoxychalcone)
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