Ergocristine

Chemical compound
IdentifiersCAS Number
  • 511-08-0 checkY
PubChem CID
  • 31116
ChemSpider
  • 28873 ☒N
UNII
  • 3E58HO2T0U
ChEMBL
  • ChEMBL446315 ☒N
CompTox Dashboard (EPA)
  • DTXSID40891858 Edit this at Wikidata
ECHA InfoCard100.007.383 Edit this at WikidataChemical and physical dataFormulaC35H39N5O5Molar mass609.727 g·mol−13D model (JSmol)
  • Interactive image
  • O=C3N1CCC[C@H]1[C@]2(O)O[C@](C(=O)N2[C@H]3Cc4ccccc4)(NC(=O)[C@@H]8/C=C7/c5cccc6c5c(c[nH]6)C[C@H]7N(C)C8)C(C)C
InChI
  • InChI=1S/C35H39N5O5/c1-20(2)34(37-31(41)23-16-25-24-11-7-12-26-30(24)22(18-36-26)17-27(25)38(3)19-23)33(43)40-28(15-21-9-5-4-6-10-21)32(42)39-14-8-13-29(39)35(40,44)45-34/h4-7,9-12,16,18,20,23,27-29,36,44H,8,13-15,17,19H2,1-3H3,(H,37,41)/t23-,27-,28+,29+,34-,35+/m1/s1 ☒N
  • Key:HEFIYUQVAZFDEE-MKTPKCENSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ergocristine is an ergopeptine and one of the ergot alkaloids.[1] As of February 24, 2010 ergocristine has been federally regulated. Because of the existing Controlled Substance Act regulatory controls on the LSD precursors lysergic acid, lysergic acid amide, ergotamine, and ergonovine, clandestine laboratory operators have sought uncontrolled sources of precursor material for the production of LSD. This has led to the illicit utilization of the precursor chemical ergocristine as a direct substitute for ergotamine and ergonovine for the illicit production of LSD. In fact, the largest clandestine LSD laboratory ever, William Leonard Pickard and Clyde Apperson, that was seized by the Drug Enforcement Administration (DEA) utilized ergocristine as the LSD precursor according to court documents.[2]

The DEA determined that ergocristine was readily available from commercial chemical suppliers. DEA had identified at least three suppliers of ergocristine, of which one distributor is located domestically; the other two are based in Germany and the Czech Republic.[3][2]

References

  1. ^ Stoll A (1952). "Recent investigations on ergot alkaloids". Fortschritte der Chemie Organischer Naturstoffe: 114–174 (159). ISBN 9783709171691.
  2. ^ a b "Control of Ergocristine, a Chemical Precursor Used in the Illicit Manufacture of Lysergic Acid Diethylamide, as a List I Chemical" (PDF). Microgram Bulletin. 43 (3): 24. 2010.
  3. ^ "DEA Diversion Control Division".
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Lysergic acid
derivativesPsychedelic
lysergamidesClavinesOther
ergolinesNatural
sources

Morning glory: Argyreia nervosa (Hawaiian Baby Woodrose), Ipomoea spp.(Morning Glory, Tlitliltzin, Badoh Negro), Rivea corymbosa (Coaxihuitl, Ololiúqui)


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