Dentatothalamic tract

Dentatothalamic tract
The cerebello-dentato-thalamo-cortical pathway. The figure depicts the pathway from the cerebellum to the motor cortex, via the ventrolateral nucleus of the thalamus.
Tractography of dentatothalamic tract.
Details
Identifiers
Latin	tractus dentatothalamicus
NeuroNames	534
NeuroLex ID	birnlex_1104
TA2	5847
FMA	72462
Anatomical terms of neuroanatomy [edit on Wikidata]

The dentatothalamic tract (or dentatorubrothalamic tract) is a tract which originates in the dentate nucleus and follows the ipsilateral superior cerebellar peduncle, decussating later on and reaching the contralateral red nucleus and the contralateral thalamus.^[1]

The term "dentatorubrothalamocortical" is sometimes used to emphasize termination in the cerebral cortex.^[2]

Additional images

3D data of the dentatothalamic tract. Reonctructed using tractography.

References

^ Operative Neurosurgery: Dentatorubrothalamic tract
^ Boiten J, Lodder J (February 1990). "Ataxic hemiparesis following thalamic infarction". Stroke. 21 (2): 339–40. doi:10.1161/01.str.21.2.339. PMID 2305412.

External links

Wikimedia Commons has media related to Dentatothalamic tract.

Krauss JK, Wakhloo AK, Nobbe F, Tränkle R, Mundinger F, Seeger W (December 1995). "Lesion of dentatothalamic pathways in severe post-traumatic tremor". Neurol. Res. 17 (6): 409–16. doi:10.1080/01616412.1995.11740353. PMID 8622792.
NIF Search - Dentatothalamic Tract via the Neuroscience Information Framework
https://web.archive.org/web/20091021004541/http://isc.temple.edu/neuroanatomy/lab/atlas/papc/

Anatomy of the cerebellum

Surface

Lobes	Anterior lobe Posterior lobe Horizontal fissure Flocculonodular lobe Flocculus Nodule Primary fissure
Medial/lateral	Vermis: anterior Central lobule Culmen Lingula posterior Folium Tuber Uvula Vallecula of cerebellum Hemisphere: anterior Alar central lobule posterior Biventer lobule Cerebellar tonsil

Grey matter

Deep cerebellar nuclei	Dentate interposed Emboliform Globose Fastigial
Cerebellar cortex	Molecular layer Stellate cell Basket cell Purkinje cell layer Purkinje cell Bergmann glia cell = Golgi epithelial cell Fañanas cell Granule cell layer Golgi cell Granule cell Unipolar brush cell Fibers: Mossy fibers Climbing fiber Parallel fiber

White matter

Internal	Arbor vitae
Peduncles	Inferior (medulla): Dorsal spinocerebellar tract Olivocerebellar tract Cuneocerebellar tract Juxtarestiform body (Vestibulocerebellar tract) Trigeminocerebellar fibers Middle (pons): Pontocerebellar fibers Superior (midbrain): Ventral spinocerebellar tract Dentatothalamic tract

Anatomy of the midbrain

Tectum
(Dorsal)

Corpora quadrigemina

Grey matter

Pretectal area

White matter

Sensory / ascending	Spinotectal tract Central tegmental tract
Motor / descending	Tectospinal tract

CSF

Cerebral aqueduct

Peduncle
(Ventral)

Tegmentum

White matter

Sensory / ascending	Lemnisci Medial Lateral Ascending MLF Vestibulo-oculomotor fibers Spinothalamic tract Anterior trigeminothalamic tract Dentatothalamic tract
Motor / descending	Rubrospinal tract Rubro-olivary tract Descending MLF

Grey matter

cranial nuclei	GSA Mesencephalic GSE Oculomotor nucleus Trochlear nucleus GVE Edinger–Westphal nucleus
Ventral tegmental area	Rostromedial tegmental nucleus
Periaqueductal gray Red nucleus Rostral interstitial nucleus of medial longitudinal fasciculus Parabrachial area Interpeduncular nucleus
Midbrain reticular formation	dorsal tegmental nucleus Raphe nuclei dorsal Reticulotegmental nucleus

Base

White / Cerebral crus	Corticospinal tract Corticobulbar tract Corticopontine tract Frontopontine fibers Temporopontine fibers
Grey / Substantia nigra	Pars compacta Pars reticulata
Surface	Superior cerebellar peduncle Decussation Interpeduncular fossa

Anatomy of the diencephalon of the human brain

Epithalamus

Surface	Pineal gland Habenula Habenular trigone Habenular commissure
Grey matter	Pretectal area Habenular nuclei Subcommissural organ

Thalamus

Surface	Stria medullaris of thalamus Thalamic reticular nucleus Taenia thalami
Grey matter/ nuclei	paired: AN Ventral VA/VL VP/VPM/VPL Lateral LD LP Pulvinar nuclei Metathalamus MG LG P cell M cell K cell midline: MD Intralaminar Centromedian Midline nuclear group Interthalamic adhesion
White matter	Mammillothalamic tract Pallidothalamic tracts Ansa lenticularis Lenticular fasciculus Thalamic fasciculus PCML Medial lemniscus Trigeminal lemniscus Spinothalamic tract Lateral lemniscus Dentatothalamic tract Acoustic radiation Optic radiation Subthalamic fasciculus Anterior trigeminothalamic tract Medullary laminae

Hypothalamus

Surface

Grey matter

Autonomic zones	Anterior (parasympathetic/heat loss) Posterior (sympathetic/heat conservation)
Endocrine	posterior pituitary: Paraventricular Magnocellular neurosecretory cell Parvocellular neurosecretory cell Supraoptic oxytocin/vasopressin other: Arcuate (dopamine/GHRH) Preoptic (GnRH) Suprachiasmatic (melatonin)
Emotion	Lateral Ventromedial Dorsomedial

White matter

afferent
efferent
- Mammillothalamic tract
- Dorsal longitudinal fasciculus

Pituitary

Posterior is diencephalon, but anterior is glandular

Subthalamus

Brain and spinal cord: neural tracts and fasciculi

Sensory

DCML

1°:	Pacinian corpuscle/Meissner's corpuscle → Posterior column (Gracile fasciculus/Cuneate fasciculus) → Gracile nucleus/Cuneate nucleus
2°:	→ sensory decussation/arcuate fibers (Posterior external arcuate fibers, Internal arcuate fibers) → Medial lemniscus/Trigeminal lemniscus → Thalamus (VPL, VPM)
3°:	→ Posterior limb of internal capsule → Postcentral gyrus

Anterolateral/
pain

Fast/lateral	1° (Free nerve ending → A delta fiber) → 2° (Anterior white commissure → Lateral and Anterior Spinothalamic tract → Spinal lemniscus → VPL of Thalamus) → 3° (Postcentral gyrus) → 4° (Posterior parietal cortex) 2° (Spinomesencephalic tract → Superior colliculus of Midbrain tectum)
Slow/medial	1° (Group C nerve fiber → Spinoreticular tract → Reticular formation) → 2° (MD of Thalamus) → 3° (Cingulate cortex)

Motor

Pyramidal

flexion: Primary motor cortex → Posterior limb of internal capsule → Decussation of pyramids → Corticospinal tract (Lateral, Anterior) → Neuromuscular junction

Extrapyramidal

flexion:	Primary motor cortex → Genu of internal capsule → Corticobulbar tract → Facial motor nucleus → Facial muscles
flexion:	Red nucleus → Rubrospinal tract
extension:	Vestibulocerebellum → Vestibular nuclei → Vestibulospinal tract
extension:	Vestibulocerebellum → Reticular formation → Reticulospinal tract
Midbrain tectum → Tectospinal tract → muscles of neck

Basal ganglia

direct:	1° (Motor cortex → Striatum) → 2° (GPi) → 3° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 4° (Thalamocortical radiations → Supplementary motor area) → 5° (Motor cortex)
indirect:	1° (Motor cortex → Striatum) → 2° (GPe) → 3° (Subthalamic fasciculus → Subthalamic nucleus) → 4° (Subthalamic fasciculus → GPi) → 5° (Lenticular fasciculus/Ansa lenticularis → Thalamic fasciculus → VL of Thalamus) → 6° (Thalamocortical radiations → Supplementary motor area) → 7° (Motor cortex)
nigrostriatal pathway:	Pars compacta → Striatum

Cerebellar

Afferent

Vestibular nuclei → Vestibulocerebellar tract → ICP → Cerebellum → Granule cell

Pontine nuclei → Pontocerebellar fibers → MCP → Deep cerebellar nuclei → Granule cell

Inferior olivary nucleus → Olivocerebellar tract → ICP → Hemisphere → Purkinje cell → Deep cerebellar nuclei

Efferent

Dentate nucleus in Lateral hemisphere/pontocerebellum → SCP → Dentatothalamic tract → Thalamus (VL) → Motor cortex

Interposed nucleus in Intermediate hemisphere/spinocerebellum → SCP → Reticular formation, or → Cerebellothalamic tract → Red nucleus → Thalamus (VL) → Motor cortex

Fastigial nucleus in Flocculonodular lobe/vestibulocerebellum → Vestibulocerebellar tract → Vestibular nuclei

Bidirectional:
Spinocerebellar

Unconscious proprioception	lower limb → 1° (muscle spindles → DRG) → 2° (Posterior thoracic nucleus → Dorsal/posterior spinocerebellar tract → ICP → Cerebellar vermis) upper limb → 1° (muscle spindles → DRG) → 2° (Accessory cuneate nucleus → Cuneocerebellar tract → ICP → Anterior lobe of cerebellum)
Reflex arc	lower limb → 1° (Golgi tendon organ) → 2° (Ventral/anterior spinocerebellar tract→ SCP → Cerebellar vermis) upper limb → 1° (Golgi tendon organ) → 2° (Rostral spinocerebellar tract → ICP → Cerebellum)