2-Oleoylglycerol

2-Oleoylglycerol

Names
IUPAC name 2-O-[(9Z)-Octadec-9-enoyl]glycerol
Systematic IUPAC name 1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate
Other names 2-Monoolein
Identifiers
CAS Number	3443-84-3 Y
3D model (JSmol)	Interactive image
ChemSpider	4478086 Y
IUPHAR/BPS	5112
PubChem CID	5319879
UNII	9A2389K694 Y
CompTox Dashboard (EPA)	DTXSID8058661
InChI InChI=1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-20(18-22)19-23/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9- Y Key: UPWGQKDVAURUGE-KTKRTIGZSA-N Y
SMILES CCCCCCCCC=CCCCCCCCC(=O)OC(CO)CO
Properties
Chemical formula	C21H40O4
Molar mass	356.547 g·mol−1
Density	0.958 g/cm3
Hazards
Flash point	> 113.0 °C (235.4 °F; 386.1 K)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

2-Oleoylglycerol (2OG) is a monoacylglycerol that is found in biologic tissues. Its synthesis is derived from diacylglycerol precursors. It is metabolized to oleic acid and glycerol primarily by the enzyme monoacylglycerol lipase (MAGL).^[1] In 2011, 2OG was found to be an endogenous ligand to GPR119.^[2] 2OG has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine.^[2]

See also

• 2-Arachidonoylglycerol
• JZL184

References